Announcement PDF Level 8 121 Castlereagh Street Sydney NSW 2000 Australia GPO Box 5015 Sydney NSW 2001 +61 2 9210 7070 info@SoulPatts.com.au SoulPatts.com.au 25 June 2026 ASX Announcement Notice of initial substantial holder for ATX Please find attached Form 603 - Notice of initial substantial holder (‘Notice’) required to be lodged under the Corporations Act 2001 (‘the Act’). The Notice sets out a technical interest which Soul Patts is deemed to hold under the Act due to holding voting power of more than 20% of the ordinary fully paid shares in Pengana Capital Group Limited (PCG). Yours sincerely Lillie Johnson Company Secretary –ENDS– This ASX announcement has been authorised for release by the Company Secretary. About Soul Patts Washington H. Soul Pattinson (“Soul Patts”) is an Australian public company that first listed on the Sydney Stock Exchange (now ASX) on 21 January 1903. With origins in owning and operating Australian pharmacies, Soul Patts has since evolved into an investment house with a diversified and uncorrelated portfolio of assets across multiple industries. Soul Patts takes a long-term approach to investing with an objective to deliver superior returns by creating capital growth and regular dividends. Through owning SOL shares, an investor gains access to the following asset classes: listed companies, private companies, emerging companies, credit, and real assets. More information: SoulPatts.com.au 603 page 2 of 8 15 July 2001 Form 603 Corporations Act 2001 Section 671B Notice of initial substantial holder To Company Name/Scheme AMPLIA THERAPEUTICS LIMITED (ASX: ATX) ACN/ARSN ACN 165 160 841 1. Details of substantial holder(1) Name WASHINGTON H. SOUL PATTINSON AND COMPANY LIMITED (Soul Patts) AND SUBSIDIARIES ACN/ARSN (if applicable) ACN 687 534 023 The holder became a substantial holder on 22/06/2026 2. Details of voting power The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in on the date the substantial holder became a substantial holder are as follows: Class of securities (4) Number of Securities Person’s votes (5) Voting power (6) Ordinary Shares Pengana Capital Group Limited (PCG) 27,544,919 27,544,919 5.37% Total 27,544,919 27,544,919 5.37% 3. Details of relevant interests The nature of the relevant interest the substantial holder or an associate had in the following voting securities on the date the substantial holder became a substantial holder are as follows: Holder of relevant interest Nature of relevant interest (7) Class and number of securities See PCG’s Notice of initial substantial holder for ATX lodged on 24 June 2026 and attached (Annexure A) 4. Details of present registered holders The persons registered as holders of the securities referred to in paragraph 3 above are as follows: Holder of relevant interest Registered holder of securities Person entitled to be registered as holder (8) Class and number of securities PCG BNP Paribas Nominees Pty Limited Pengana Capital Limited (PCL) RELEVANT INTEREST DUE TO HOLDING VOTING POWER OF MORE THAN 20% IN PCG 5. Consideration The consideration paid for each relevant interest referred to in paragraph 3 above, and acquired in the four months prior to the day that the substantial holder became a substantial holder is as follows: Holder of relevant interest Date of acquisition Consideration (9) Class and number of securities See PCG’s Notice of initial substantial holder for ATX lodged on 24 June 2026 and attached (Annexure A) 603 page 3 of 8 15 July 2001 6. Associates The reasons the persons named in paragraph 3 above are associates of the substantial holder are as follows: Name and ACN/ARSN (if applicable) Nature of association See list of subsidiaries of Soul Patts as disclosed in the "Controlled Entities" Note of the last Annual Report. 7. Addresses The addresses of persons named in this form are as follows: Name Address Soul Patts, WHSP Holdings Pty Limited, Soul Patts Holdings Pty Limited and subsidiaries Level 8, 121 Castlereagh Street, Sydney, NSW 2000 Pengana Capital Group Limited Governor Phillip Tower, Level 27/1 Farrer Pl, Sydney NSW 2000 Signature print name Lillie Johnson Capacity Company Secretary sign here date 25 June 2026 DIRECTIONS (1) If there are a number of substantial holders with similar or related relevant interests (eg. a corporation and its related corporations, or the manager and trustee of an equity trust), the names could be included in an annexure to the form. If the relevant interests of a group of persons are essentially similar, they may be referred to throughout the form as a specifically named group if the membership of each group, with the names and addresses of members is clearly set out in paragraph 7 of the form. (2) See the definition of “associate” in section 9 of the Corporations Act 2001. (3) See the definition of “relevant interest” in sections 608 and 671B(7) of the Corporations Act 2001. (4) The voting shares of a company constitute one class unless divided into separate classes. (5) The total number of votes attached to all the voting shares in the company or voting interests in the scheme (if any) that the person or an associate has a relevant interest in. (6) The person’s votes divided by the total votes in the body corporate or scheme multiplied by 100. (7) Include details of: (a) any relevant agreement or other circumstances by which the relevant interest was acquired. If subsection 671B(4) applies, a copy of any document setting out the terms of any relevant agreement, and a statement by the person giving full and accurate details of any contract, scheme or arrangement, must accompany this form, together with a written statement certifying this contract, scheme or arrangement; and (b) any qualification of the power of a person to exercise, control the exercise of, or influence the exercise of, the voting powers or disposal of the securities to which the relevant interest relates (indicating clearly the particular securities to which the qualification applies). See the definition of “relevant agreement” in section 9 of the Corporations Act 2001. (8) If the substantial holder is unable to determine the identity of the person (eg. if the relevant interest arises because of an option) write “unknown”. (9) Details of the consideration must include any and all benefits, money and other, that any person from whom a relevant interest was acquired has, or may, become entitled to receive in relation to that acquisition. Details must be included even if the benefit is conditional on the happening or not of a contingency. Details must be included of any benefit paid on behalf of the substantial holder or its associate in relation to the acquisitions, even if they are not paid directly to the person from whom the relevant interest was acquired. 603 page 4 of 8 15 July 2001 Annexure A Form 603 – Notice of initial substantial holder from Pengana Capital Group Limited (ACN 059 300 426) and its subsidiaries. This and the following 4 pages form Annexure A referred to in Form 603 – Notice of initial substantial holder by Soul Patts. Name: Lillie Johnson Capacity: Company Secretary Signature: Date: 25 June 2026 603 page1/2 15July 2018 Form 603 Corporations Act 2001 Section 671B Notice of initial substantial holder To Company/registered scheme/notified foreign passport fund name ACN/ARSN/APFRN NFPFRN (if applicable) 1. Details of substantial holder (1) Name ACN/ARSN/APFRN (if applicable) NFPFRN (if applicable) The holder became a substantial holder on 2. Details of voting power The total number of votes attached to all the voting shares or interests in the company, scheme or fund that the substantial holder or an associate (2) had a relevant interest (3) in on the date the substantial holder became a substantial holder are as follows: 3. Details of relevant interests The nature of the relevant interest the substantial holder or an associate had in the following voting securities on the date the substantial holder became a substantial holder are as follows: 4. Details of present registered holders The persons registered as holders of the securities referred to in paragraph 3 above are as follows: 5. Consideration The consideration paid for each relevant interest referred to in paragraph 3 above, and acquired in the four months prior to the day that the substantial holder became a substantial holder is as follows: Class of securities (4) Number of securities Person's votes (5) Voting power (6) Holder of relevant interest Nature of relevant interest (7) Class and number of securities Holder of relevant interest Registered holder of securities Person entitled to be registered as holder (8) Class and number of securities Holder of relevant interest Date of acquisition Consideration (9) Class and number of securities Cash Non-cash ABN: 16 165 160 841 Annexure A Annexure A AMPLIA THERAPEUTICS LIMITED / 22 06 2026 / Fully Paid Ordinary Shares 27,544,919 27,544,919 5.37% Annexure B Annexure B Annexure C 603 page2/2 15July 2018 6. Associates The reasons the persons named in paragraph 3 above are associates of the substantial holder are as follows: 7. Addresses The addresses of persons named in this form are as follows: Signature print name capacity signhere date / / DIRECTIONS (1) If there are a number of substantial holders with similar or related relevant interests (eg. A corporation and its related corporations, or the manager and trustee of an equity trust), the names could be included in an annexure to the form. If the relevant interests of a group of persons are essentially similar, they may be referred to throughout the form as a specifically named group if the membership of each group, with the names and addresses of members is clearly set out in paragraph 7of the form. (2) See the definition of "associate" in section 9 of the Corporations Act 2001. (3) See the definition of "relevant interest" in sections 608 and 671B(7) of the Corporations Act 2001. (4) The voting shares of a company constitute one class unless divided into separate classes. (5) The total number of votes attached to all the voting shares or interests in the company, scheme or fund (if any) that the person or an associate has a relevant interest in. (6) The person's votes divided by the total votes in the body corporate, scheme or fund multiplied by 100. (7) Include details of: (a) any relevant agreement or other circumstances by which the relevant interest was acquired. If subsection 671B(4) applies, a copy of any document setting out the terms of any relevant agreement, and a statement by the person giving full and accurate details of any contract, scheme or arrangement, must accompany this form, together with a written statement certifying this contract, scheme or arrangement; and (b) any qualification of the power of a person to exercise, control the exercise of, or influence the exercise of, the voting powers or disposal of the securities to which the relevant interest relates (indicating clearly the particular securities to which the qualification applies). See the definition of "relevant agreement" in section 9 of the Corporations Act 2001. (8) If the substantial holder is unable to determine the identity of the person (eg. if the relevant interest arises because of an option) write "unknown". (9) Details of the consideration must include any and all benefits, money and otherwise, that any person from whom a relevant interest was acquired has, or may, become entitled to receive in relation to that acquisition. Details must be included even if the benefit is conditional on the happening or not of a contingency. Details must be included of any benefit paid on behalf of the substantial holder or its associate in relation to the acquisitions, even if they are not paid directly to the person from whom the relevant interest was acquired. Name and ACN/ARSN/APFRN (if applicable) and NFPFRN (if applicable) Nature of association Name Address N/A Annexure D Keith McLachlan Director, Pengana Capital Ltd 24 06 2026 Details of Substantial Holder ACN Pengana Capital Group Limited 059 300 426 Pengana Capital Limited 103 800 568 Pengana Investment Management Limited 063 081 612 Pengana International Equities Limited 107 462 966 Holder of Relevant Interest Registered Holder of Securities and person entitled to be Registered as Holder Nature of Relevant Interest Class and numberof shares Pengana Capital Group Limited As below Pengana Capital Group has a relevant interest in the said securities as it wholly owns Pengana Capital Limited and Pengana Investment Management Limited Pengana Capital Limited BNP Paribas Nominees Pty Limited (ACN 084 150 023) on behalf of Pengana Capital Limited Relevant interest arising as a result of Pengana Capital Limited having power to control the voting and/ or disposal of securities pursuant to position held as an investment manager of various unit trusts. 27,544,919 Pengana Investment Management Limited BNP Paribas Nominees Pty Limited (ACN 084 150 023) on behalf of Pengana Investment Management Limited Relevant interest arising as a result of Pengana Investment Management Limited having power to control the voting and/ or disposal of securities pursuant to position held as an investment manager of various unit trusts. Pengana International Equities Limited BNP Paribas Nominees Pty Limited (ACN 084 150 023) on behalf of Pengana International Equities Limited Pengana Capital Group has a relevant interest in the said securities as it wholly owns Pengana Investment Management Limited who is the investment manager of Pengana International Equities Limited Annexure B Annexure A Date of Change Nature of Change No of Shares Consideration Holder 01-Apr-26 Purchase 2,000,000.00 518,464.00 $ Pengana Capital Limited 23-Apr-26 Purchase 1,000,000.00 157,500.00 $ Pengana Capital Limited 24-Apr-26 Purchase 800,000.00 128,640.00 $ Pengana Capital Limited 27-Apr-26 Purchase 187,664.00 30,608.00 $ Pengana Capital Limited 28-Apr-26 Purchase 800,000.00 130,160.00 $ Pengana Capital Limited 29-Apr-26 Purchase 212,336.00 33,973.76 $ Pengana Capital Limited 18-Jun-26 Purchase 1,000,000.00 115,900.00 $ Pengana Capital Limited 22-Jun-26 Purchase 2,734,045.00 344,763.07 $ Pengana Capital Limited Annexure D Pengana Capital Group Limited Suite 1, Level 27, Governor Phillip Tower, 1 Farrer Place, Sydney, NSW2000, Australia Pengana Capital Limited Suite 1, Level 27, Governor Phillip Tower, 1 Farrer Place, Sydney, NSW2000, Australia Pengana Investment Management Limited Suite 1, Level 27, Governor Phillip Tower, 1 Farrer Place, Sydney, NSW2000, Australia Pengana International Equities Limited Suite 1, Level 27, Governor Phillip Tower, 1 Farrer Place, Sydney, NSW2000, Australia Annexure C