Announcement PDF Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities 1 / 7 Announcement Summary Entity name AMPLIA THERAPEUTICS LIMITED Date of this announcement Wednesday September 09, 2026 The +securities the subject of this notification are: Total number of +securities to be issued/transferred ASX +security code Security description Total number of +securities to be issued/transferred Issue date New class - code to be confirmed Zero Exercise Price Options Expiry Date 9 Sep 2031 2,830,629 09/09/2026 Refer to next page for full details of the announcement +Other securities issued under an +employee incentive scheme that are not intended to be quoted on ASX Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities 2 / 7 Part 1 - Entity and announcement details 1.1 Name of entity AMPLIA THERAPEUTICS LIMITED We (the entity named above) give notice of the issue, conversion or payment up of the following unquoted +securities. 1.2 Registered number type ABN Registration number 16165160841 1.3 ASX issuer code ATX 1.4 The announcement is 1.5 Date of this announcement 9/9/2026 New announcement Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities 3 / 7 Part 2 - Issue details 2.1 The +securities the subject of this notification are: 2.2a This notification is given in relation to an issue of +securities in a class which is not quoted on ASX and which: does not have an existing ASX security code ("new class") +Other securities issued under an +employee incentive scheme that are not intended to be quoted on ASX Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities 4 / 7 Part 3C - number and type of +securities the subject of this notification (new class) ASX +security code New class - code to be confirmed +Security description Zero Exercise Price Options Expiry Date 9 Sep 2031 +Security type Options ISIN code Date the +securities the subject of this notification were issued 9/9/2026 Will all the +securities issued in this class rank equally in all respects from their issue date? Were any of the +securities issued to +key management personnel (KMP) or an +associate? Provide details of the KMP or +associates being issued +securities. Name of KMP Name of registered holder Number of +securities Dr Chris Burns CHRISTOPHER JOHN BURNS 687,772 Jane Bell MRS JANE CATHERINE JOCELYN BELL 642,857 Dr Robert Peach ANDREA MARIE PEACH & ROBERT JAMES PEACH <PEACH FAMILY A/C> 500,000 Dr Warwick Tong WARWICK TONG 500,000 Brett Carter JOYCE LAM <BioSeer Family Trust> 500,000 Have you received confirmation from ASX that the terms of the +securities are appropriate and equitable under listing rule 6.1? Please provide a URL link for a document lodged with ASX setting out the material terms of the +securities being issued. https://ampliatx.com/announcements/7651968 Options Details +Security currency AUD - Australian Dollar Exercise price AUD 0.00000000 Expiry date 9/9/2031 No Yes Yes Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities 5 / 7 Details of the existing class of +security that will be issued upon exercise or conversion of this new class of company option ATX : ORDINARY FULLY PAID Please provide a URL link for a document lodged with ASX detailing the terms of the +employee incentive scheme or a summary of the terms https://ampliatx.com/announcements/7651968 Any other information the entity wishes to provide about the +securities the subject of this notification ZEPOs issued to Directors following approval of shareholders at Annual General Meeting held 28 August 2026. Issue details Number of +securities 2,830,629 Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities 6 / 7 Part 4 - +Securities on issue Following the issue, conversion or payment up of the +securities the subject of this notification, the +securities of the entity will comprise: The figures in parts 4.1 and 4.2 below are automatically generated and may not reflect the entity's current issued capital if other Appendix 2A, Appendix 3G or Appendix 3H forms are currently with ASX for processing. 4.1 Quoted +securities (Total number of each +class of +securities issued and quoted on ASX) ASX +security code and description Total number of +securities on issue ATXOA : OPTION EXPIRING 31-OCT-2027 90,299,589 ATX : ORDINARY FULLY PAID 513,312,014 4.2 Unquoted +securities (Total number of each +class of +securities issued but not quoted on ASX) ASX +security code and description Total number of +securities on issue ATXAD : OPTION EXPIRING 30-SEP-2028 EX $0.30 818,006 ATXAE : OPTION EXPIRING 30-SEP-2028 EX NIL 447,000 ATXAAI : OPTION EXPIRING 20-DEC-2028 EX $0.23 5,250,000 ATXAAF : OPTION EXPIRING 05-JUN-2028 EX $0.132 5,000,000 ATXAAJ : OPTION EXPIRING 01-MAY-2029 EX NIL 240,384 ATXAG : OPTION EXPIRING 15-JUL-2031 EX NIL 1,272,099 ATXAF : OPTION EXPIRING 15-JUL-2028 EX $0.19 987,592 New class - code to be confirmed : Zero Exercise Price Options Expiry Date 9 Sep 2031 2,830,629 Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities Appendix 3G - Notification of issue, conversion or payment up of unquoted equity securities 7 / 7 Part 5 - Other Listing Rule requirements 5.1 Were the +securities issued under an exception in Listing Rule 7.2 and therefore the issue did not need any security holder approval under Listing Rule 7.1? 5.1a Select the number of the applicable exception in Listing Rule 7.2 13 Yes